| 1. | The complement system is controlled by cells that secrete neutralizing proteins.
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| 2. | In the complement system low C3 levels are associated with systemic lupus erythematosus
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| 3. | If this occurs, an immune response mediated by the complement system will occur.
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| 4. | Also, C4 and C2 cleavage goes unchecked, resulting in auto-activation of the complement system.
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| 5. | These mechanisms include antimicrobial peptides called defensins, pattern recognition receptors, and the complement system.
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| 6. | Nonetheless, it is known that XNAs and the complement system are not primarily involved.
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| 7. | IgA does not usually activate the complement system and is not involved with phagocytosis.
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| 8. | Other basic immune mechanisms, including phagocytosis and the complement system, evolved in ancient eukaryotes.
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| 9. | The M-protein aids in immune evasion by inhibiting phagocytosis and inactivating the complement system.
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| 10. | Microbes may activate the complement system directly and complement component C3b bind to microbes.
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